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Ofertas de Profesores de universidades y de la enseñanza superior en Oslo (Noruega)

Phd Fellowship In Nuclear Architecture In Laminopathy Models - Klm Forskningsseksjonen Rh

Clasificación del trabajo: Profesionales científicos e intelectuales : Profesionales de la enseñanza : Profesores de universidades y de la enseñanza superior : Profesores de universidades y de la enseñanza superior.

Professionals : Teaching professionals : University and higher education teachers : University and higher education teachers

Descripción de la oferta de trabajo:

Oslo University Hospital is a highly specialized hospital in charge of extensive regional and local hospital assignments.

As Scandinavia's largest hospital, we carry out more than 1.2 million patient treatments each year.

The hospital has a nationwide responsibility for a number of national and multi-regional assignments, and has several national centers of competence.

Oslo University Hospital is responsible for approximately 50 percent of all medical and health care research conducted at Norwegian hospitals, and is a significant role player within the education of a large variety of health care personnel. A 3-year PhD position is available at the Department of Immunology and Transfusion Medicine, Oslo University Hospital - Rikshospitalet.

The position is related to the project Good fat - bad fat: regulation of adipose tissue distribution and implications for metabolic health" funded by the South-Eastern Norway Regional Health Authority.The Laboratory of Professor Philippe Collas seeks a motivated PhD student candidate to study fundamental mechanisms controlling nuclear architecture under healthy and pathological conditions.

Project group leader and supervisor for the position: Dr.

Coen Campsteijn.

The candidate will be able to draw on cross-disciplinary expertise in the areas of nuclear architecture, laminopathy and cancer models, adipose tissue physiology, cell proliferation and differentiation, genome stability, genomics, membrane dynamics, and computational biology.

Research infrastructure includes access to (live-cell) microscopy, proteomics, flow cytometry/FACS, sequencing, etc.Job location: Department of Molecular Medicine, Institute of Basic Medical Sciences, University of OsloThe application must include:- Application letter including statement of motivation for this PhD position- CV summarizing education, positions and relevant work experience including research- Complete list of publications (do not include articles themselves)- Copies of educational certificates- List of 2-3 references stating relation to the candidate, with contact information- Application material should be in EnglishOnly electronic applications through WebCruiter will be considered.Job description

  • The project focuses on the role of lamins and their interactors in nuclear architecture.

    The aim is to gain mechanistic understanding of how lamin mutations that cause lipodystrophies adversely affect nuclear architecture and integrity, and adipocyte fitness.

  • The project uses adipocyte differentiation as main model and interrogates fat depot-specific effects of mutations on nuclear membrane associated factors, mechanosensitivity and nuclear integrity, proliferation and senescence, genome organization and signalling.
  • The candidate will use advanced molecular cell biology, live-cell imaging, genetics and proteomics approaches.
  • Master's degree with a background in molecular cell biology or biochemistry.
  • Experience with mammalian cell culture, transgenesis and microscopy techniques will be advantageous
  • Eagerness to integrate and work in a cross-disciplinary team
  • Proficiency in spoken and written English
Education field
  • Bioingeniørfag
Education level
  • Høyskole / Universitet, Cand Mag / Siv
Personal qualities
  • Strong drive for fundamental mechanistic research
  • Motivation for the position and commitment to carry out high-level research
  • Ability to take scientific initiatives and troubleshoot complex challenges
  • Collaboration skills
  • Excellent communication skills, including proficiency in spoken and written English
  • Personal suitability for the position
We offer